Moderate alcohol consumption appears to increase the risk of breast cancer in women. Total mortality is reduced with moderate alcohol consumption but not with heavy alcohol consumption; the cardiovascular benefit is offset by cirrhosis, cancer, and injuries. The amount of alcohol associated with the lowest mortality appears to be 2 drinks per day in men and 1 drink or fewer per day in women. Moderate alcohol consumption reduces the risk of developing diabetes, but heavy alcohol consumption may increase the risk. The cardiovascular benefit becomes important in men older than 40 years and in women older than 50 years. The risk of hypertension is increased with 3 or more drinks daily.
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A condition characterised by a pathologic pattern of alcohol use causing a serious impairment in social or occupational functioning; also defined by the Joint Committee of the National Council on Alcoholism and Drug Dependence & the American Society of Addiction Medicine as a “primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterised by … distortions in thinking, most notably denial.” A simpler, operational definition is persistent drinking that interferes with the person’s health, legal position, interpersonal relationships, or means of livelihood. Alcoholism is characterised by the regular intake of ≥75 g/day of alcohol.
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